News 15 Sep 2026 New DNDi report: Implementing Article 9.5 of the WHO Pandemic Agreement – building on current policy and practice for publicly funded R&D
Scientific articles 15 Aug 2026 Identification of new Trypanosoma cruzi-specific protein synthesis inhibitors by using a developed high-throughput in vitro translation assay International Journal for Parasitology: Drugs and Drug Resistance
Scientific articles 5 Aug 2026 ICH E21: from landmark guidance to specific action for maternal and child health
Scientific articles 3 Aug 2026 A Phase IIa, Proof-of-Concept, Placebo-Controlled, Randomised Trial to Investigate the Efficacy and Safety of Oxfendazole as a Macrofilaricidal Drug in Adults Harbouring Lymphatic Filarial Worms Infectious Diseases and Therapy
In the media 1 Aug 2026 End of painful injections as Kenya set to adopt new 14-day Kala-azar treatment Daily Nation
In the media 30 Jul 2026 WHO approves new shorter, less painful Kala-azar treatment for East Africa New Vision
Viewpoints 30 Jul 2026 Ten years after WHO recognition, mycetoma remains one of the world’s most neglected diseases Stat News
In the media 21 Jul 2026 How Scientists Can Revive Global Health Drug Development Think Global Health
Scientific articles 19 Aug 2026 A serological method’s ability to distinguish treatment regimens by assessing early antibody decline in Chagas patients: insights from E1224 data The Journal of Infectious Diseases
Scientific articles 18 Sep 2025 Structure–activity relationships of fenarimol analogues with potent in vitro and in vivo activity against Madurella mycetomatis, the main causative agent of eumycetoma RSC Medicinal Chemistry
Scientific articles 8 Sep 2025 Quantifying anti-trypanosomal treatment effects in chronic indeterminate Chagas disease: a secondary analysis of individual patient data from two proof-of-concept trials The Lancet Microbe
Scientific articles 11 Aug 2025 Collaborative synthesis for neglected diseases through the Open Synthesis Network: structure–activity relationships of arylaminopyrazoles as Chagas disease treatments ACS Infectious Diseases
Scientific articles 3 Aug 2025 Noma as a neglected tropical disease: an opportunity to reconsider neglect in global health BMJ Global Health
Scientific articles 14 Jul 2025 Barbituric acid derivatives as covalent inhibitors of Leishmania braziliensis dihydroorotate dehydrogenase Journal of Medicinal Chemistry
Scientific articles 9 Jul 2025 Antitrypanosomal quinazolines targeting lysyl-tRNA synthetase show partial efficacy in a mouse model of acute Chagas disease Science Translational Medicine
Scientific articles 26 Jun 2025 Validated LC-MS/MS method for quantifying the antiparasitic nitroimidazole DNDI-0690 in preclinical target site PK/PD studies Biomedical Chromatography
Scientific articles 25 Jun 2025 “Female Genital Schistosomiasis: Translational Challenges and Opportunities”: Outputs and actions from a consultative, collaborative and translational workshop Parasitology
Scientific articles 28 May 2025 Pharmacokinetics and pharmacodynamics of fosravuconazole, itraconazole, and hydroxyitraconazole in Sudanese patients with eumycetoma The Journal of Infectious Diseases
Scientific articles 26 May 2025 Traitement oral de la trypanosomiase humaine africaine : faisabilité dans les communautés du littoral Guinéen Santé Publique
Scientific articles 15 May 2025 Quantitative analysis of DNDI-6174 using UPLC-MS/MS: A preclinical target site pharmacokinetic study Journal of Chromatography B
Scientific articles 13 May 2025 Pharmacokinetic-pharmacodynamic modeling of benznidazole and its antitrypanosomal activity in a murine model of chronic Chagas disease PLOS Neglected Tropical Diseases
Scientific articles 9 May 2025 Efficient constitution of a library of rotenoid analogs active against Trypanosoma cruzi from a digitalized plant extract collection RSC Advances
Scientific articles 9 May 2025 Epidemiological, clinical and etiological treatment aspects in the Chagas clinic of the municipality of Comapa – Jutiapa, Guatemala Acta Tropica
Scientific articles 29 Apr 2025 Effectiveness and safety of fexinidazole for gambiense human African trypanosomiasis and exploration of adherence in outpatients: A phase IIIb, prospective, open-label, non-randomised, cohort study The Lancet Global Health
Scientific articles 29 Apr 2025 Fexinidazole as a new oral treatment for human African trypanosomiasis due to Trypanosoma brucei rhodesiense: A prospective, open-label, single-arm, Phase II–III, non-randomised study The Lancet Global Health
