Together with the World Health Organization (WHO), we launched the Global Antibiotic Research and Development Partnership (GARDP) in 2016.

GARDP logo

GARDP is a not-for-profit organization that develops new treatments to fight drug-resistant infections that pose the greatest threat to health, while working to ensure responsible use and sustainable access.

In 2019, GARDP became an independent legal entity, following a successful incubation by DNDi, during which time we provided GARDP’s initial governance, scientific environment, and infrastructure, as well as support for resource mobilization, communication, finance, and human resources.

Both organizations continue to share R&D expertise and capacity (including discovery, pharmaceutical development, translational science, pharmacovigilance, and quality assurance); access to an international network, as in-country implementation of GARDP’s programmes is supported by DNDi regional offices and through a joint office in Southern Africa; and a common approach on global health policy for promoting and contributing to public health needs-driven R&D and access.

‘We’re proud to have provided the environment to enable GARDP to kickstart its mission to deliver antimicrobial research for patients. We look forward to a strong collaboration in sharing resources and knowledge with GARDP in the future, for the ultimate benefit of the populations served by GARDP and DNDi.’

Dr Marie-Paule Kieny, DNDi Board Chair

Antibiotic-resistant infections are already responsible for 1.2 million deaths a year

Antibiotics have saved millions of lives and radically improved our well-being, but they have been used so extensively that many are losing their ability to defeat bacteria.

GARDP’s key priorities

  • Children’s antibiotics: GARDP is working to accelerate the development of new, improved and adapted antibiotics to treat drug-resistant infections in children, including sepsis in babies.
  • Serious bacterial infections: GARDP is accelerating the development of new treatments to address bacterial infections in hospitalized people for which there are limited or no treatment options.
  • Sexually transmitted infections: GARDP is accelerating the development of new treatments for difficult-to-treat and drug-resistant sexually transmitted infections, including gonorrhoea.
  • Discovery & exploratory: GARDP is screening chemical libraries to identify compounds that can be transformed into treatments for drug-resistant infections; identifying new chemical entities for preclinical and clinical development; and working with partners on a range of educational and knowledge sharing activities in antibiotic drug R&D, including REVIVE.

Learn more about GARDP’s work to tackle this growing global public health threat.

Incubation by DNDi



  • GARDP started the first of its clinical trials: a clinical trial in Kenya confirming the dose and safety of fosfomycin to treat neonatal sepsis.
  • GARDP completed phase 1 pharmacokinetic and safety study on zoliflodacin to treat drug-resistant gonorrhoea, allowing appropriate dose selection for the pivotal phase 3 trial.
  • Over 80 researchers from 11 countries gathered in New Delhi to kick-off a global observational study for newborns with sepsis. Data generated from the study will be used to evaluate future interventions for this vulnerable population.
  • Several new public and private partnerships were formed, including with Takeda Pharmaceutical Company Limited and Eisai, Sandoz (the Novartis generics division), and the University of Liverpool.


  • By early 2017, GARDP had secured EUR 6.5 million in seed funding, facilitated 11 expert meetings in six countries on specific disease areas, regional issues, project reviews, and sustainable access; and built a team of 17 people by the end of the year.
  • In May, a Scientific Advisory Committee of experts in various disciplines within infectious diseases and microbiology was set up.
  • With their expert review and DNDi’s Board of Directors’ approval, GARDP launched four programmes: neonatal sepsis; sexually transmitted infections; antimicrobial memory recovery, evaluation and exploratory research; and paediatric antibiotics.
  • In July, GARDP signed its first partnering deal with Entasis Therapeutics to develop a new treatment for drug-resistant gonorrhoea.
  • In September, the German government hosted a pledging event for GARDP, a number of countries and foundations pledged more than EUR 56 million to GARDP.


  • GARDP was launched in May 2016.
  • GARDP received seed funding and pledges from the governments of Germany, Netherlands, South Africa, Switzerland, and the United Kingdom as well as from the medical humanitarian organization Médecins Sans Frontières / Doctors Without Borders (MSF).