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Home > Diseases
Mosquito icon

Dengue

Creating a global partnership to tackle a rapidly spreading climate-sensitive disease

Home > Diseases
Mosquito icon

Dengue

Creating a global partnership to tackle a rapidly spreading climate-sensitive disease

  • Overview
  • Facts

We are partnering with dengue-endemic countries to find a safe, affordable, and effective treatment for dengue. Through this global collaboration we are working on joint projects to advance the pre-clinical development of new drug candidates and run clinical trials to test the most promising ones.

Dengue is mostly spread by the bite of the Aeades aegypti mosquito. Some people have no symptoms, but dengue can also cause flu-like symptoms including fever, nausea, vomiting, rashes, eye pain and muscle, joint, or bone pain. There are no specific drugs to treat dengue, and there is only limited use of vaccines. The lack of treatment options increases the risk of developing severe dengue – which is potentially fatal.

Dengue is the most widely distributed and rapidly spreading mosquito-borne viral disease in the world, fuelled by climate change, rapid urbanization and population growth. Dengue is classified by the World Health Organization as one of the top ten threats to public health.

Icon people in front of globe
0 billion
people in 129 countries at risk of infection
Icon parasite
0 million
infections per year
Icon people
0 %
increase in number of cases from 1990 to 2019
Icon globe
0 %
of world’s population predicted to be at risk of infection by 2080
SEE DISEASE FACTS

‘It’s everywhere and there’s nothing we can do about it.’

Ma Tan Jhii Lian, infected by dengue twice in just three months in Malacca, Malaysia
READ MORE

What we have achieved

We are bringing together partners in dengue-endemic countries to find urgently needed treatments for dengue. So far, we have partnered with Thailand, India, Brazil, and Malaysia, with more countries joining soon.

What we’re doing for people with dengue

Together with our partners, we have started preclinical studies and will be starting clinical trials aiming to deliver an affordable and accessible treatment within five years. We are also working together on diagnostics and regulatory and access strategies, as well as jointly raising funds and mobilizing resources.

Making medical history for neglected patients

We develop urgently needed treatments for neglected patients and ensure they’re affordable, available, and adapted to the communities who need them

Doctor diagnosing a man in a village with his hands on the man's neck

Sleeping sickness

Transmitted by the bite of a tsetse fly and causes severe neurological disorders

We delivered a revolutionary new drug to replace toxic treatments, and have ongoing trials to eliminate this disease

Young boy sitting on a hospital bed being examined by a nurse

Chagas disease

Causes heart and vital organ damage, after people are bitten by blood-sucking bugs

We delivered the first-ever treatment for children; now we’re searching for new drug candidates and working to boost access to care

Girl with skin lesions on her nose

Cutaneous leishmaniasis

Leaves disfiguring, life-long scars that lead to severe social stigma

We’re working to develop safer, shorter treatments for this disabling disease

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Hepatitis C

Millions are left without treatment even though effective drugs exist

We’ve delivered a treatment as simple, safe, and effective as the best drugs available today – at a fraction of the cost 

Girl looking over a fence

Visceral leishmaniasis

Is one of the world’s biggest parasitic killers, spread by the bites of sandflies

We’re working to develop a new generation of treatments to replace drugs that are painful, ineffective, and cause side effects

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COVID-19

Devasting and deadly to many, there’s too little research to help the most vulnerable

We’re accelerating research by coordinating clinical trials in low-resource settings and bringing together partners

Father walking in rural village with a cane and holding his son's hand

Filaria: river blindness

Lead to unbearable itching, disfiguring skin lesions, and even blindness

We’re working to develop a safe, effective, and affordable drug for the prevention and treatment of this debilitating disease

Patient medical examination

Cryptococcal meningitis

Without treatment, deadly for thousands of people with advanced HIV

We’re working to improve access to life-saving treatments and developing an easier-to-use formulation

Sleeping sickness

Chagas disease

Cutaneous leishmaniasis

Hepatitis C

Visceral leishmaniasis

COVID-19

Filaria: river blindness

Cryptococcal meningitis

VIEW ALL DISEASES

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