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  • DNDi_Logo_No-Tagline_Full Colour
  • Our work
    • Diseases
      • Sleeping sickness
      • Visceral leishmaniasis
      • Cutaneous leishmaniasis
      • Chagas disease
      • Parasitic worms
      • Mycetoma
      • Dengue
      • Paediatric HIV
      • Cryptococcal meningitis
      • Hepatitis C
      • Pandemic preparedness
      • Antimicrobial resistance
    • Research & development
      • R&D portfolio & list of projects
      • Drug discovery
      • Translational research
      • Clinical trials
      • Registration & access
      • Treatments delivered
    • Advocacy
      • Open and collaborative R&D
      • Transparency of R&D costs
      • Pro-access policies and IP
      • Children’s health
      • Gender equity
      • Climate change
      • AI and new technologies
  • Networks & partners
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      • Our partners
      • Partnering with us
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      • Chagas Platform
      • Dengue Alliance
      • HAT Platform
      • LEAP Platform
      • redeLEISH Network
    • DNDi worldwide
      • DNDi Switzerland
      • DNDi Eastern Africa
      • DNDi Japan
      • DNDi Latin America
      • DNDi North America
      • DNDi South Asia
      • DNDi South-East Asia
      • DNDi West and Central Africa
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Home

Research and development

We put neglected communities at the heart of drug R&D

Home

Research and development

We put neglected communities at the heart of drug R&D

Advancing medical innovation from laboratory bench to patient bedside

Our teams have been working since 2003 to address gaps in the traditional biomedical R&D system that lead to serious unmet medical needs for neglected patients. Acting as a ‘conductor of a virtual orchestra’, DNDi collaborates with research partners around the world at all stages of the R&D process. Together, we’ve discovered, developed, and delivered new treatments that reduce illness, suffering, and death from some of the world’s most neglected diseases.

Drug discovery

Translational research

Clinical trials

Registration and access

Project portfolio

We are working on more than 40 research and treatment access projects, including 21 focused on identifying or developing new chemical entities.

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Treatments delivered

We have delivered thirteen new treatments for six deadly diseases, saving millions of lives.

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Scientific articles

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Scientific articles
9 Jan 2026

Target product profile for the development of pediatric formulations of new drugs for the treatment of children with T. cruzi infection

PLOS Neglected Tropical Diseases
Scientific articles
12 Jan 2026

Dengue therapeutics consortium 2025: a global collaboration in action

BMJ Global Health
Scientific articles
10 Jan 2026

Liposomal antimicrobials in the fight against bacterial and fungal pathogens: Clinical successes and development challenges

International Journal of Pharmaceutics X
Scientific articles
9 Jan 2026

Global health is in crisis: to reach neglected patients, we need to reimagine medical research

BMJ Global Health
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Target product profiles (TPPs)

TPPs serve to ensure that all products are designed from the start for the people and places that need them by describing the ideal specifications needed for a treatment.

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Events

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10-21 November 2025

Belém, Brazil

COP30

9-13 November 2025

Toronto, Canada

ASTMH 2025

6 November 2025, 3:00 PM Nairobi

Online

Bridging the gap between research and policy for NTDs amid a changing funding landscape

4-6 November 2025

Antwerp, Belgium & online

65th ITM Colloquium

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International non-profit developing safe, effective, and affordable treatments for the most neglected patients.

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