Scientific articles 17 Dec 2025 Kronopolitides A–F, a family of 36-membered polyol macrolides with antiparasitic activity against Chagas disease Journal of Natural Products
In the media 15 Dec 2025 The biggest mosquito-borne disease in the world has a cure. There’s just one problem Vox
News 4 Dec 2025 Dr Javid Abdelmoneim, Datuk Dr Mahathar bin Abd Wahab, Dr Taruna Madan, Violet Naanyu, and Dr Mario Santos Moreira join the Board of Directors at DNDi
In the media 2 Dec 2025 “Como si me comiera desde dentro”: la enfermedad que ataca los huesos en el norte de Kenia EFE
Scientific articles 2 Dec 2025 The development of a global research agenda and individual participant data platform for visceral leishmaniasis: challenges and future opportunities Parasites & Vectors
Press releases 27 Nov 2025 International seminar explores the development of treatments for dengue for populations not covered by vaccines
News 26 Nov 2025 DNDi statement on the approval of the Instituto Butantan’s dengue vaccine and the need for a dengue treatment
Scientific articles 25 Nov 2025 Bidirectional interaction between liposomal amphotericin B pharmacokinetics and parasite dynamics in patients with post-kala-azar dermal leishmaniasis: Potential implications for optimal dosing Clinical Pharmacology & Therapeutics
Videos 24 Nov 2025 Interview with Dr Pauline Williams, new DNDi Scientific Advisory Committee (SAC) Chair
Scientific articles 20 Nov 2025 Safety, tolerability and pharmacokinetics of DNDI-6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants British Journal of Clinical Pharmacology
Scientific articles 17 Dec 2025 Kronopolitides A–F, a family of 36-membered polyol macrolides with antiparasitic activity against Chagas disease Journal of Natural Products
Scientific articles 2 Dec 2025 The development of a global research agenda and individual participant data platform for visceral leishmaniasis: challenges and future opportunities Parasites & Vectors
Scientific articles 25 Nov 2025 Bidirectional interaction between liposomal amphotericin B pharmacokinetics and parasite dynamics in patients with post-kala-azar dermal leishmaniasis: Potential implications for optimal dosing Clinical Pharmacology & Therapeutics
Scientific articles 20 Nov 2025 Safety, tolerability and pharmacokinetics of DNDI-6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants British Journal of Clinical Pharmacology
Scientific articles 4 Nov 2025 Host-derived molecules as novel chagas disease biomarkers: hypercoagulability markers and extracellular vesicles Methods in Molecular Biology
Scientific articles 30 Oct 2025 Target product profile and discovery and development path for novel cryptococcal disease treatments Journal of Infection
Scientific articles 7 Oct 2025 Core outcome measurement set for clinical trials in dengue: an international Delphi consensus study (DEN-CORE) The Lancet Infectious Diseases
Scientific articles 30 Sep 2025 New regimens of benznidazole for the treatment of chronic Chagas disease in adult participants in indeterminate form or with mild cardiac progression (NuestroBen study): protocol for a phase III randomised, multicentre non-inferiority clinical trial BMJ Open
Scientific articles 29 Sep 2025 Performance evaluation of rapid diagnostic tests for Chagas disease in Jutiapa, Guatemala Journal of the Brazilian Society of Tropical Medicine
Scientific articles 22 Sep 2025 Mass balance, pharmacokinetics, metabolism, and excretion of radiolabeled acoziborole, a potential novel treatment for human African trypanosomiasis, following single microtracer oral dose to humans Antimicrobial Agents and Chemotherapy
Scientific articles 18 Sep 2025 Structure–activity relationships of fenarimol analogues with potent in vitro and in vivo activity against Madurella mycetomatis, the main causative agent of eumycetoma RSC Medicinal Chemistry
Scientific articles 8 Sep 2025 Quantifying anti-trypanosomal treatment effects in chronic indeterminate Chagas disease: a secondary analysis of individual patient data from two proof-of-concept trials The Lancet Microbe
Scientific articles 11 Aug 2025 Collaborative synthesis for neglected diseases through the Open Synthesis Network: structure–activity relationships of arylaminopyrazoles as Chagas disease treatments ACS Infectious Diseases
Scientific articles 3 Aug 2025 Noma as a neglected tropical disease: an opportunity to reconsider neglect in global health BMJ Global Health
Scientific articles 14 Jul 2025 Barbituric acid derivatives as covalent inhibitors of Leishmania braziliensis dihydroorotate dehydrogenase Journal of Medicinal Chemistry
