The DNDi Latin America office was opened in 2004. With the primary aim to support regional R&D activities for Chagas disease, malaria, and leishmaniasis, the Latin American office also undertakes advocacy and communications activities to increase neglected diseases awareness in the region.
Access: Alongside Colombia’s Ministry of Health, the Chagas Access pilot project completed its third and final year, with positive results leading to similar access programmes being initiated in Guatemala, Brazil, and the USA
Partnerships: Built a robust regional drug discovery platform with two Brazilian universities, USP and UNICAMP, for Chagas and visceral leishmaniasis; collaborated with the Andean Region Health Organization focusing on access to treatments for hepatitis C
Completed an in vitro study to test the susceptibility of Leishmania infantum to the drug miltefosine
Started a retrospective study to assess the effectiveness of amphotericin B for the treatment of HIV/VL-coinfected patients in Brazil, in collaboration with 7 public institutions, the Health Surveillance Secretariat of the Brazilian Ministry of Health, and PAHO/WHO
Held a successful 5thredeLEISH meeting in Rio de Janeiro with a focus on the harmonization of clinical trials for cutaneous leishmaniasis
Completed the BENDITA study of benznidazole to treat Chagas disease in three sites in Bolivia, leading to results in early 2019
Completed recruitment for the Fexi 012 study of fexinidazole to treat Chagas in five sites in Spain
Hosted a Chagas Platform meeting in Bolivia with a focus on research priorities and signatures for the Santa Cruz letter, calling on governments and international organizations to step up their efforts to eliminate Chagas as a public health problem
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