Logo MycetOS project

The Mycetoma Open Source project (MycetOS) uses an Open Pharma approach to discover new treatments (new chemical entities, or NCEs) for fungal mycetoma (eumycetoma).

The project will drive lead optimization of compounds targeting Madurella mycetomatis, the predominant causative agent of eumycetoma. Using this radically open approach, MycetOS will identify new drug candidates in a transparent and inclusive way.

The project will progress discovery efforts through community-driven, in-kind scientific contributions and a robust, fully transparent online presence. All ideas and results will be published immediately in real time to an open-access database.

Intellectual property

All work generated by MycetOS will be published immediately and in real time to the public domain database and thus remain free of the constraints of intellectual property.

Infographic explaining the MycetOS project

Project updates

2019

A list of current targets for Open Pharma project MycetOS has been compiled and opportunities given to researchers interested in working on them. Two participating institutions from the Open Synthesis Network have received preliminary data and are working to identify new compounds with potential activity against mycetoma. 

News & publications

Factsheet

Screenshot MycetOS fact sheet

Open Source Mycetoma
2018

More information

  • Dedicated subreddit forum for transparent, interactive discussion
  • Data sharing and key project files will be shared on github

For further information, please contact Dr Ben Perry (bperry@dndi.org) or join the project communications on Twitter (@MycetOS).

Launch participants

Associate Professor Wendy van de Sande from Erasmus University, Rotterdam, Netherlands; Associate Professor Mat Todd at the University of Sydney, Australia; Ben Perry, Senior Discovery Manager, DNDi.