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Home > Scientific articles
2024-08-15

A standardized clinical database for research in Chagas disease: The NHEPACHA network

PLOS Neglected Tropical Diseases

by González Martínez A, Losada-Galván I, Gabaldón-Figueira JC, Martínez-Peinado N, Saraiva RM, Fernández ML, Ramsey JM, Noya-González O, Alarcón de Noya B, Schijman AG, Berón S, Abril M, Gascón J, Sosa-Estani S, Pinazo M-J, Alonso-Padilla J, Hasslocher-Moreno AM. PLOS Neglected Tropical Diseases 2024, 18(8): e0012364. doi: 10.1371/journal.pntd.0012364.

Summary: The NHEPACHA Iberoamerican Network, founded on the initiative of a group of researchers from Latin American countries and Spain, aims to establish a research framework for Chagas disease that encompasses diagnosis and treatment. The authors of the manuscript present a questionnaire, based on a consensus of expert members of this network, to gather relevant data on epidemiological, clinical, diagnostic, and therapeutic aspects of Chagas disease. The questionnaire is intended to collect high-quality standardized data, which can be used interchangeably by the different research centers that make up the NHEPACHA network. Alongside this, the network has provided a clinical protocol, with the aim of facilitating comparability among published studies and the development of therapeutic response and progression markers.

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Chagas disease

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