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Home > Diseases
hepatitis-c icon

Hepatitis C

Meeting the needs of millions still waiting for affordable treatment

Home > Diseases
hepatitis-c icon

Hepatitis C

Meeting the needs of millions still waiting for affordable treatment

  • Overview
  • Facts
  • Projects & achievements

We have developed a simple-to-use, affordable cure and tested new strategies to link patients to lifesaving treatment and care. We are also working to foster the political will needed for wide-scale roll-out of test-and-treat strategies together with allies in the Hepatitis C Partnership for Control and Treatment (Hepatitis C PACT).

Hepatitis C is caused by the blood-borne hepatitis C virus that can lead to chronic liver disease, cirrhosis, cancer, and, if not treated, death. Symptoms can take decades to develop and most people living with the disease do not know they are infected. As a result, hepatitis C is a silent epidemic.

Recent years have seen a revolution in medical innovation for hepatitis C, which can now be cured with just 8 to 24 weeks of safe, simple treatment. However, just 13% of people living with the disease worldwide have benefited. In many countries, high prices remain a major barrier for ‘test-and-treat’ strategies that have the potential to eliminate hepatitis C altogether.

 
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DOWNLOAD FACTSHEET
SEE DISEASE FACTS

‘Hepatitis C is a “silent epidemic” because people are unaware of their infection and go untreated for years.’

Sasikala Siva, DNDi Clinical Project Manager in Kuala Lumpur, Malaysia

What we have achieved

We delivered a new treatment that is equal to the best hepatitis C drugs, at a fraction of the cost.

Read more in our Annual Report
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Treatment Delivered

Ravidasvir + sofosbuvir

An affordable cure to leave no one behind. We have developed a new simple-to-use, affordable treatment for hepatitis C to increase access and minimize financial burden on patients and health systems. Trial results in Malaysia showed 97% of people treated were cured.

What we are doing for people living with hepatitis C

We are working to help foster an enabling environment for improved availability of hepatitis C diagnostics and treatments in low- and middle-income countries and supporting innovative ‘test-and-treat’ programmes in several countries.

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Hepatitis C news & resources

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News
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Publications
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News
4 Mar 2025

2024 R&D programmes in review: Hepatitis C

Publications
11 Jul 2024

DNDi 2023 Annual Report

Statements
21 May 2024

DNDi’s briefing note for 77th World Health Assembly

Scientific articles
20 May 2024

Population pharmacokinetics of ravidasvir in adults with chronic hepatitis C virus infection and impact of antiretroviral treatment

Antimicrobial Agents and Chemotherapy
See all news

Making medical history for neglected patients

We develop urgently needed treatments for neglected patients and ensure they’re affordable, available, and adapted to the communities who need them

Young boy sitting on a hospital bed being examined by a nurse

Chagas disease

Causes heart and vital organ damage, after people are bitten by blood-sucking bugs

We delivered the first-ever treatment for children; now we’re searching for new drug candidates and working to boost access to care

Patient medical examination

Cryptococcal meningitis

Without treatment, deadly for thousands of people with advanced HIV

We’re working to improve access to life-saving treatments and developing an easier-to-use formulation

Girl with skin lesions on her nose

Cutaneous leishmaniasis

Leaves disfiguring, life-long scars that lead to severe social stigma

We’re working to develop safer, shorter treatments for this disabling disease

Doctor with young patient in hospital setting

Dengue

Rapidly spreading climate-sensitive disease with no specific treatment

We’re building a global partnership with dengue-endemic countries to develop a first treatment

Father walking in rural village with a cane and holding his son's hand

Filaria: river blindness

Lead to unbearable itching, disfiguring skin lesions, and even blindness

We’re working to develop a safe, effective, and affordable drug for the prevention and treatment of this debilitating disease

Young man standing in the street

Hepatitis C

Millions are left without treatment even though effective drugs exist

We’ve delivered a treatment as simple, safe, and effective as the best drugs available today – at a fraction of the cost 

Woman standing in front of her door house in a rural village in Sudan

Mycetoma

Often ends in amputation​, after people get infected from stepping on a thorn

We conducted the world’s first trial for an alternative to current treatments, which are toxic and difficult to administer

Mother holding her baby in her arms smiling

Paediatric HIV

Without treatment, half of children die before their second birthday

We’ve developed a strawberry-flavoured treatment to meet the needs of children long neglected by the global HIV response

Healthcare workers in a hospital

Pandemic Preparedness

The COVID-19 pandemic intensified global health inequalities

We’re bringing together partners and accelerating research to prepare for future viral pandemics in low-resource settings

Doctor diagnosing a man in a village with his hands on the man's neck

Sleeping sickness

Transmitted by the bite of a tsetse fly and causes severe neurological disorders

We delivered a revolutionary new drug to replace toxic treatments, and have ongoing trials to eliminate this disease

Girl looking over a fence

Visceral leishmaniasis

Is one of the world’s biggest parasitic killers, spread by the bites of sandflies

We’re working to develop a new generation of treatments to replace drugs that are painful, ineffective, and cause side effects

Chagas disease

Cryptococcal meningitis

Cutaneous leishmaniasis

Dengue

Filaria: river blindness

Hepatitis C

Mycetoma

Paediatric HIV

Pandemic Preparedness

Sleeping sickness

Visceral leishmaniasis

VIEW ALL DISEASES

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