DNDi Latin America organized a series of events with conferences, discussions and meetings. The final event, the Partners’ Meeting, took place on June 8th 2016 in Rio de Janeiro, Brazil. Participants from the field of research & development on neglected diseases, including international scientists, product developers, policy-makers, and civil society organizations, participated in the events in order to promote the best science for the most neglected.
Partners’ Meeting
Date: June 8, 2016
Venue: Hotel Rio Othon Palace Av. Atlantica, 3264 – Copacabana
Opening Ceremony
Time: 08:30-10:00
| Welcome | Marcel Tanner, DNDi Board Chair and Professor and Chair of Epidemiology & Medical Parasitology, University of Basel & Federal Institute of Technology, Switzerland |
| Opening Addresses | Alejandro Gaviria Uribe, Minister of Health & Social Protection of Colombia Jorge Bermudez, Vice President of Health Production & Innovation, Fiocruz, Minister of Health of Brazil Innovation & access for neglected populations, a dynamic approach towards 2023 Bernard Pécoul, Executive Director, DNDi Key challenges and prospects for Latin America Joël Keravec, Regional Executive Director, DNDi Latin America |
| Closing Remarks | Joël Keravec, Regional Executive Director, DNDi Latin America |
Panel Discussions
| 10:30-11:30 |
Session 1: Innovation & access for Chagas disease Chair: Mercedes Tatay, International Medical Secretary, MSF Switzerland Respondents: – Sergio Sosa-Estani, Director, Insituto Fatala Chaben – Nancy Dominga da Costa, President of the Rio Chagas Association – Marcelo Paganini, Executive Director, Mundo Sano – Isabela Ribeiro, Head of Chagas Clinical Program, DNDi -Oscar Bernal, Director of the Master’s in Public Health Program, Los Andes University | |
| 11:30-12:30 |
Session 2: Innovation & access for Leishmaniasis Chair: Renato Alves, Head of the Vector Born Disease Unit, Ministry of Health Brazil Respondents: – Ivano Dario Velez, Director, PECET, University of Antioquia – Ana Nilce Elkhoury, Regional Advisor of Leishmaniasis, PAHO – Gustavo Romero, Professor, University of Brazil – Moacir Zini, Patient Representative, Mato Grosso State – Byron Arana, Head of Cutaneous Leishmaniasis, DNDi | |
| 14:00-14:45 | Keynote Discussion Zika, Chagas, Hepatitis C: From emergencies to Sustainable Innovation & Access in Latin America and the Rest of the World Chair: Marcel Tanner, DNDi Board Chair, Professor & Chair of Epidemiology & Medical Parasitology, University of Basel & Federal Institute of Technology, Switzerland Respondents: – Nick White, Professor of Tropical Medicine, Mahidol University – Nila Heredia, President, ASOFAMD and Former Minister of Health & Sports, Bolivia – Noor Hisham Abdullah, Director General of Health, Ministry of Health, Malaysia | |
| 14:45-15:45 | Session 3: The role of innovative funding initiatives for global health needs Chair: Dr Els Torreele, Director, Access to Essential Medicines, Open Society Foundations Respondents: – Elkin Echeverri, Director of Planning and Strategy, Ruta N – João Paulo Pieroni, Head of Pharmaceutical Products, BNDES – Draurio Barreira, Manager, Tuberculosis, Strategy and Results, UNITAID – Joël Keravec, Regional Executive Director, DNDi Latin America – Suerie Moon, Research Director at the Harvard School of Public Health | |
| 15:45-16:45 | Session 4: How to address emerging public health challenges & priorities Chair: Nirmal K. Ganguly, Advisor and Professor, Translational Health Science & Technology Institute, India National Institute of Immunology Respondents: – Claudia Vaca, Pharmacoepidemiologist, Professor at the Department of Pharmacy, National University, Colombia – Manica Balasegaram, Director, Global Antibiotic R&D (GARD, DNDi) Partnership – Yasser Mohamed Fayed, Business Development Director, Pharco Pharmaceuticals – Jorge Bermudez, Vice President of Health Production and Innovation, Fiocruz – Bernard Pécoul, Executive Director, DNDi |
Closing Ceremony
| 17:00-18:00 | Closing Remarks: Awards and Farewell Chair: Prof Marcel Tanner, Chair – Project of the Year – Partnership of the Year – Innovative Funding Mechanism |
Chagas Platform Meeting & Workshops
Workshops
Date: June 6, 2016
Venue: Hotel Rio Othon Palace Av. Atlantica, 3264 – Copacabana
| Workshop 1 – 08:30-13:00 Meeting Room: Copacabana A | Discovery of new drugs for leishmaniasis and Chagas disease Moderator:Eric Chatelain, DNDi / Fabiana Barreira, DNDi |
| Workshop 2 – 08:30-12:30 Meeting Room: Copacabana B | Mini-course: Preparation of scientific articles Moderator: Ronald Henry, Centers for Disease Control and Prevention / Marina Boni, DNDi |
| Workshop 3 – 08:30-13:00 Meeting Room: Bossa | Strengthening the Chagas education for health careers Moderator: Edgardo Moretti, Universidad Nacional de Córdoba, Argentina / Jorge Pedro Martin, DNDi |
| Workshop 4 – 08:30-13:30 Meeting Room: Pontal CLOSED MEETING | Update on qPCR validation and quality control for diagnosis and monitoring of Chagas disease patients Moderator: Zaida Yadón, WHO/OMS / Alejandro Schijman, INGEBI-CONICET / Erika Correira, DNDi |
| Workshop 5 – 14:00-18:30 Meeting Room: Copacabana A | Theoretical and practical workshop on the diagnosis, treatment and monitoring of children with congenital Chagas disease – RED PEDCHAGAS Moderator: Jaime Altcheh, Hospital de Niños R. Gutiérrez de Buenos Aires / Christina Alonso Vega, DNDi |
| Workshop 6 – 14:00-18:30 Meeting Room: Copacabana B | Interface between civil society and NGOs to tackle NTDs: Prospectives on opportunites and challenges Moderator: Alberto Novaes Ramos Jr., Universidade Federal do Ceará / Marina Certo, DNDi |
| Workshop 6 – 14:00-18:30 Meeting Room: São Conrado CLOSED MEETING | New research fields and guidelines for Chagas disease Moderator: Sergio Sosa-Estani, INP Fatela Chaben, MoH Argentina, Andrea Marchiol, DNDi |
| Workshop 7 – 14:00-16:00 Meeting Room: Bossa | Barriers and strategies of access to treatments for Leishmaniasis Moderator: Carolina Batista DNDi / Joelle Rode, DNDi |
| Workshop 8 – 16:15-18:30 Meeting Room: Bossa | Current status and perspective of Leishmaniasi diagnosis in the American region Moderator: Zaida Yadón WHO/OMS / Mady Malheiros Barbeitas, DNDi |
Sessions
Date: June 7, 2016
Venue: Hotel Rio Othon Palace Av. Atlantica, 3264 – Copacabana
| 8:30-09:30 | Discovery of new drugs for leishmaniasis and Chagas disease Moderator: Eric Chatelain, DNDi, Geneva Speakers: – Luiz Carlos Dias, UNICAMP – Carolina Borsoi Moraes, LNBio – Facundo García-Bournissen, Hospital de Niños R. Gutiérrez de Buenos Aires – John Kelly, London School of Hygiene & Tropical Medicine – Momar Ndao, McGill University | |
| 9:30-10:30 | Vaccines for Chagas disease: strategies and current studies overview Moderator: Maria Elena Bottazzi, Sabin Vaccine Institute Product Development Partnership Speakers: – Kathryn Jones, Sabin Vaccine Institute e Texas Children’s Hospital Center for Vaccine Development – Igor Almeida, University of Texas at El Paso – UTEP – Ricardo Gazzinelli, Fundação Oswaldo Cruz – Fiocruz |
INTERVAL – COFFEE BREAK
| 10:45-12:30 | The new landscape for chronic patients based on current knowledge Moderator: Sergio Sosa-Estani, INP Fatala Chaben – ANLIS – MSN, Argentina Speakers: – Rodolfo Viotti, Hospital Eva Perón, Buenos Aires, Argentina – Anis Rassi Junior, Hospital Anis Rassi – Goiânia |
LUNCH
| 14:00-15:00 |
Updates on clinical trials studies for Chagas disease – where we are and future prospects Moderator: Rodolfo Viotti, Hospital Eva Perón Speakers: – Jaime Altcheh, Hospital de Niños R. Gutiérrez de Buenos Aires – Israel Molina, HU Vall Hebron-PROSICS Barcelona – María Gabriela Álvarez, Hospital Eva Perón, Buenos Aires – Tania C. de Araújo-Jorge, IOC – Fiocruz – Joaquim Gascon, ISGlobal |
| 15:00-15:50 |
New trends and challenges for Chagas: Integrative therapy approach and oral Chagas disease Moderator: Israel Molina, HU Vall Hebron-PROSICS, Barcelona Speakers: – Andréa Silvestre de Sousa, INI – Fiocruz – Belkisyolé Alarcón de Noya, Inst. Medicina Tropical, UCV – Ana Yecê das Neves Pinto, IEC – Fiocruz |
COFFEE BREAK
| 16:00-17:30 |
Transforming evidence into public health policy: operational research and challenges in access Moderator: Lucia Brum, MSF Brazil Speakers: – Silvia Moriana, Coalición Global de la Enfermedad de Chagas – Renato Alves, Secretaria de Vigilância em Saúde do Ministério da Saúde, Brasil – Cynthia Spillmann, Programa Nacional de Chagas del Ministerio de Salud de la Nación, Argentina – Eduin Pachón Abril, Ministerio de Salud y Protección Social, Colombia) |
| 17:30-17:40 |
Closing remarks and follow up Jorge Pedro Martin, DNDi / Carolina Batista DNDi / Fabiana Barreira, DNDi |
| 18:00-22:30 | Social Cocktail Solar Real Santa Teresa – transfer 6pm from the hotel lobby |
RedeLeish Meeting
Date: June 7, 2016
Venue: Hotel Rio Othon Palace Av. Atlantica, 3264 – Copacabana
| 08:30-09:15 |
Feedback from workshops and closed meetings – Piero Olliaro, TDR/OMS – Ana Rabello, Fiocruz – Marina Boni, DNDi – Jadel Kratz, DNDi |
| 09:15-09:45 |
Status of clinical studies and portfolio of DNDi CL Byron Arana, DNDi |
INTERVAL
| 10:00-11:00 | Methods for implementing more economical clinical trials Piero Olliaro, TDR/OMS (WHO) |
| 11:00-11:30 | Clinical trials Walter Reed Army Institute: Paromomycin cream and Gentamicin Max Grogl, U.S. Naval Medical Research Unit No. 6 (NAMRU-6) |
| 11:30-12:00 | State of the art: Nanotechnology and development of local treatments Bartira Bergmann, Universidade Federal do Rio de Janeiro |
| 12:00-12:30 | State of the Art: Topical formulations for the treatment of CL Antonia Franco, Instituto Nacional de Pesquisa da Amazônia |
LUNCH
| 14:00-14:30 | State of the art: Development of HMP as a leishmanicide agent Edilene Oliveira, UFPA, Universidade Federal do Pará |
| 14:30-15:00 | Clinical trial of pharmacokinetics of miltefosine in adults and children María del Mar Castro, CIDEIM – Centro Internacional de Entrenamiento e Investigaciones Médicas |
| 15:00-15:30 | Preliminary results of circulating Leishmania species identification study in the states of Pará, Acre and Mato Grosso Lourdes Garcez, Instituto Evandro Chagas, Ministério da Saúde |
COFFEE BREAK
| 15:45-16:15 | Update of the rapid test development for the diagnosis of CL Isra Cruz, Foundation of Innovative New Diagnostics (FIND) |
| 16:15-16:30 | Lessons learned from the network model to approach clinical trials in CL and the applicability of this model in the Old World Farhad Handjani, Shiraz University of Medical Sciences |
| 16:30-16:50 | Webforum: Operation and discussions Mady Malheiros Barbeitas, redeLEISH Coordinator, DNDi Latin America |
| 16:50-17:10 | WorldLeish 6 Jorge Alvar, DNDi |
| 17:00-17:30 | Closing remarks and follow up Byron Arana, DNDi / Joelle Rode, DNDi Latin America |
| 18:00-22:30 | Social Cocktail Solar Real Santa Teresa – transfer 6pm from the hotel lobby |
At the meeting, DNDi recognized the work of Latin American partners for NTD research.
The Innovative Funding Mechanism Award
Ruta N Medellín, an organization based in Medellin, Colombia, which focuses on knowledge as a primary source for research and development, was awarded the Innovative Funding Mechanism Award for its funding of leishmaniasis.
The Partnership of the Year Award
The Partnership of the Year Award was presented to LOLA, a Latin American Lead Optimization Programme. The LOLA project uses an international collaborative approach, working with UNICAMP (University of Campinas) with partners in the USA (AbbVie) and Europe (LMPH, University of Antwerp, Belgium) to carry out early stage drug discovery and sets a precedent for all emerging neglected disease endemic countries.
