Editors: Swinney DC, Pollastri MP; series editors: Mannhold R, Buschmann H, Holenz J.
Summary: A drug discovery reference to the crippling tropical diseases that affect more than 1 billion people. The book includes information on the common approaches and the most important factors that lead to the development of new drugs for treating tropical diseases. Individual chapters review 12 neglected tropical diseases that are grouped by infectious agent, from viruses to bacteria to eukaryotic parasites. For each of these diseases, the book explains the unmet medical need and explores the current and potential drug discovery strategies. The book also includes information on potential drug compounds derived from natural products.
Chapters with DNDi co-authors:
Onchocerciasis drug discovery
by Hawryluk N, Scandale I.
Designing drugs to target trypanosoma cruzi, the etiological agent of Chagas disease: When chemistry needs biology
by Keenan M, Chatelain E.