2013-09-19

Complexes of Trypanosoma cruzi sterol 14alpha-demethylase (CYP51) with two pyridine-based drug candidates for Chagas disease: Structural basis for pathogen-selectivity

J. Biol. Chem.

by Hargrove TY, Wawrzak Z, Alexander PW, Chaplin JH, Keenan M, Charman SA, Perez CJ, Waterman MR, Chatelain E and Lepesheva GI. J. Biol. Chem., September 2013.

Click here to access the article

Latest scientific articles

Stay connected

Get our latest news, personal stories, research articles, and job opportunities.

International non-profit developing safe, effective, and affordable treatments for the most neglected patients.

Complexes of Trypanosoma cruzi sterol 14alpha-demethylase (CYP51) with two pyridine-based drug candidates for Chagas disease: Structural basis for pathogen-selectivity

Latest scientific articles

Identification of new Trypanosoma cruzi-specific protein synthesis inhibitors by using a developed high-throughput in vitro translation assay

ICH E21: from landmark guidance to specific action for maternal and child health

A Phase IIa, Proof-of-Concept, Placebo-Controlled, Randomised Trial to Investigate the Efficacy and Safety of Oxfendazole as a Macrofilaricidal Drug in Adults Harbouring Lymphatic Filarial Worms

A serological method’s ability to distinguish treatment regimens by assessing early antibody decline in Chagas patients: insights from E1224 data

Stay connected

Learn more

Get in touch

Support us

Work with us