by Torreele E, Royce C, Don R, Sevcsik AM, Croft S. PLoS Med, June 2006, 3(6):e282; author reply e284.
Summary: In this correspondence, the authors address the challenges set to the global health audience to address neglected tropical diseases affecting the poor and powerless in resource-poor settings. To tackle the gang of four, adequate and field-adapted health tools must be available, and governments must prioritize needs-driven R&D for those diseases where no such tools exist.