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  • Our work
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      • Cryptococcal meningitis
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      • Dengue
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Home > Research and development > Portfolio

Sleeping sickness 

SCYX-2035811

objective

Progress a backup nitroimidazole into pre-clinical development

project start
Jun 2011
project status
Completed

last phase of drug development

Discovery project phase
Drug Discovery
Translation project phase
Translational research
clinical trials icon
Clinical trials
Treatment Access
Registration & access

updated 31 Aug 2015

The nitroimidazole backup programme for HAT identified SCYX-2035811 as a suitable candidate for further exploration, and although initial results in animal models had shown excellent activity, further studies showed the doses tested to give insufficient cure. Given the progress of fexinidazole (Phase II/ III) and SCYX-7158 (Phase I), further development was put on hold in 2013, and the project has now been stopped.

Partners & service providers

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Funding

  • Germany - Federal Ministry of Education and Research (BMBF) through KfW
  • Spain - Spanish Agency for International Development Cooperation (AECID)
  • Switzerland - Swiss Agency for Development and Cooperation (SDC)
  • The Netherlands - Dutch Ministry of Foreign Affairs (DGIS)
  • UK - UK International Development
​
  • Médecins Sans Frontières International
  • Other private foundations and individuals
​

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