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Home > Our people > Leadership > R&D
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Sabine Specht

Sabine Specht

Head of Filarial Disease, DNDi

  • Sabine Specht

Sabine joined DNDi in October 2017. She leads the development and disease area strategy and manages the filarial projects throughout all stages of the clinical development process for new treatments for filarial infections. She has a long track record working in the field of filarial diseases and comes to DNDi from the Institute for Laboratory Animal Science, Vetsuisse Faculty, University of Zurich, CH. Prior to that she spent 12 years as a senior scientist in basic and applied research at the Institute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn, Germany.

Sabine has been active in filarial diseases for more than 15 years covering preclinical drug development in model systems and translation into humans, leading to a strong expertise clinical trials in endemic countries. In addition, her lab accomplished new insights into host-parasite interactions, which are visible in her active publication record. She is a member for several editorial boards for parasitology journals and is appointed board member of the German Society for Parasitology (DGP) and the association of biological sciences (VBIO).

Sabine graduated in Biology (Zoology, Biochemistry) from the University of Hamburg, and completed her PhD at the Bernhard-Nocht-Institute for Tropical Medicine, Hamburg in 2005.

Featured news & publications

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  • Helminth infections: Enabling the World Health Organization Road Map
  • Was ist Flussblindheit & wie können wir diese Krankheit bekämpfen?
  • Comparison of the macrofilaricidal efficacy of oxfendazole and its isomers against the rodent filaria Litomosoides sigmodontis
  • ‘Out of sight’: our work on river blindness featured in German magazine GEO
  • Flussblindheit: Die tückische Infektionskrankheit, die Menschen das Augenlicht raubt
  • Discovery of substituted di(pyridin-2-yl)-1,2,4-thiadiazol-5-amines as novel macrofilaricidal compounds for the treatment of human filarial infections
  • Filarial nematode phenotypic screening cascade to identify compounds with anti-parasitic activity for drug discovery optimization
  • Drug development for the treatment of onchocerciasis: Population pharmacokinetic and adverse events modeling of emodepside
  • Tropenkrankheiten: „Auf diese Weise werden Armutskreisläufe kreiert“
  • Onchocerciasis drug development: from preclinical models to humans

Featured events

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  • World NTD Day 2023: Snack & Talk about NTDs
  • ICTMM 2020
  • 22nd Drug Design & Development Seminar
  • Anti-Helmintics: Drugs, Resistance & Vaccines V
  • 3rd World Conference on Pharmacometrics (WCoP)

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