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DNDi - Best Science for the Most Neglected 20 Years
  • DNDi - Best Science for the Most Neglected 20 Years
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Home > Our people > Leadership > R&D
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Sabine Specht

Sabine Specht

Head of Filarial Disease, DNDi

  • Sabine Specht

Sabine joined DNDi in October 2017. She leads the development and disease area strategy and manages the filarial projects throughout all stages of the clinical development process for new treatments for filarial infections. She has a long track record working in the field of filarial diseases and comes to DNDi from the Institute for Laboratory Animal Science, Vetsuisse Faculty, University of Zurich, CH. Prior to that she spent 12 years as a senior scientist in basic and applied research at the Institute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn, Germany.

Sabine has been active in filarial diseases for more than 15 years covering preclinical drug development in model systems and translation into humans, leading to a strong expertise clinical trials in endemic countries. In addition, her lab accomplished new insights into host-parasite interactions, which are visible in her active publication record. She is a member for several editorial boards for parasitology journals and is appointed board member of the German Society for Parasitology (DGP) and the association of biological sciences (VBIO).

Sabine graduated in Biology (Zoology, Biochemistry) from the University of Hamburg, and completed her PhD at the Bernhard-Nocht-Institute for Tropical Medicine, Hamburg in 2005.

Featured news & publications

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  • Perspective on schistosomiasis drug discovery: Highlights from a schistosomiasis drug discovery workshop at Wellcome Collection, London, September 2022
  • Helminth infections: Enabling the World Health Organization Road Map
  • Was ist Flussblindheit & wie können wir diese Krankheit bekämpfen?
  • Comparison of the macrofilaricidal efficacy of oxfendazole and its isomers against the rodent filaria Litomosoides sigmodontis
  • ‘Out of sight’: our work on river blindness featured in German magazine GEO
  • Flussblindheit: Die tückische Infektionskrankheit, die Menschen das Augenlicht raubt
  • Discovery of substituted di(pyridin-2-yl)-1,2,4-thiadiazol-5-amines as novel macrofilaricidal compounds for the treatment of human filarial infections
  • Filarial nematode phenotypic screening cascade to identify compounds with anti-parasitic activity for drug discovery optimization
  • Drug development for the treatment of onchocerciasis: Population pharmacokinetic and adverse events modeling of emodepside
  • Tropenkrankheiten: „Auf diese Weise werden Armutskreisläufe kreiert“

Featured events

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  • ECTMIH 2023
  • ASTMH 2023
  • 2023 COR-NTD Annual Meeting
  • Grand Challenges Annual Meeting 2023
  • Molecular helminthology meeting 2023

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Doctors talking with patient in hospital

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Drug discovery activities

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Community worker talking with people in a rural village

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DNDi South-East Asia

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DNDi Southern Africa

Bernard Pécoul discussing with Joanne Liu at an event

DNDi Switzerland

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