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Home > Our people > Leadership > R&D
EricChatelain2019

Dr Eric Chatelain

Head of Drug Discovery Programme, DNDi

Dr Chatelain joined DNDi in July 2007 as a senior project manager focusing on screening and discovery projects for new drugs for the treatment of human African trypanosomiasis (HAT), leishmaniasis and Chagas disease.

Prior to joining DNDi, Dr Chatelain held various positions at Spirig Pharma Ltd., a Swiss-based company developing dermatology drugs. Most recently, he served as the Spirig Pharma’s Head of Preclinical Research.

Dr Chatelain completed postdoctoral fellowships at the Imperial Cancer Research Fund, in London, UK and the Friedrich Miescher Institute in Basel, Switzerland.

He earned his PhD in Biochemistry at the National Institute of Applied Sciences, Lyon France.

Featured news & publications

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  • Pharmacokinetic-pharmacodynamic modeling of benznidazole and its antitrypanosomal activity in a murine model of chronic Chagas disease
  • Early assessment of antibodies decline in Chagas patients following treatment using a serological multiplex immunoassay
  • In vivo bioluminescence imaging reveals differences in Leishmania infantum parasite killing kinetics by antileishmanial reference drugs
  • Further preclinical characterization of molnupiravir against SARS-CoV-2: Antiviral activity determinants and viral genome alteration patterns
  • Generation and evaluation of protease inhibitor-resistant SARS-CoV-2 strains
  • Bioluminescence imaging reveals enhanced SARS-CoV-2 clearance in mice with combinatorial regimens
  • Short-course combination treatment for experimental chronic Chagas disease
  • DNDI-6174 is a preclinical candidate for visceral leishmaniasis that targets the cytochrome bc1
  • Preclinical data do not support the use of amiodarone or dronedarone as antiparasitic drugs for Chagas disease at the approved human dosing regimen
  • State-of-the-art in the drug discovery pathway for Chagas disease: A framework for drug development and target validation

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  • PAGE 2022 Meeting
  • Chagas Platform Meeting 2020

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