The Drug Design & Development Seminar is organized by the German Society for Parasitology, in collaboration with Universität Bern, DNDi, and LMU Munich.
Sessions
Development of alternative treatments for filarial diseases
Date: Tuesday, 12 July 2022
Time: 9:20-11:00
Keynote: Sabine Specht, Head of Filarial Disease, DNDi
Chair: Lucienne Tritten, University of Zurich, Switzerland
| Resolution of PZQ interaction with a parasitic flatworm ion channel Jonathan S. Marchant, Medical College of Wisconsin, USA |
| Pre-clinical development of Corallopyronin A – a novel natural product active against filarial nematodes Kenneth Pfarr, University Hospital Bonn, Germany |
| The molecular targets of macrocyclic lactones in the horse parasite Parascaris univalens Claude L. Charvet, INRAE, Université de Tours, France |
Natural selection on transmission investment facilitates the spread of drug resistance in Plasmodium falciparum
Date: Friday, 15 July 2022
Time: 9:00-10:40
Keynote: Matthias Marti, University of Zurich, Switzerland
Chair: Sabine Specht, Head of Filarial Disease, DNDi
| Characterisation of Alp1 and Alp2b as transmission-blocking targets of Plasmodium Yukino Kobayashi, Justus-Liebig University Giessen, Germany |
| Protein abundance and folding rather than the redox state of Kelch13 determine the artimisinin susceptibility of Plasmodium falciparum Marcel Deponte, Technical University of Kaiserslautern, Germany |
| Preclinical Studies to support the development of M5717, a P. falciparum Elongation Factor 2 Inhibitor Thomas Spangenberg, Global Health Institute of Merck, Eysins, Switzerland |
