by Ngugi C, Nyaoke BA, Kingwara L, Akinyi P, Mmbone M, Egondi TW, Nyangweso GM, Broadhurst H, Kornmann G, Mathur R, Bettiol E. PLOS Global Public Health 2026, 6(2): e0005479. doi:10.1371/journal.pgph.0005479
Summary: Accurate prevalence estimates are essential for the public health control of Chlamydia trachomatis and Neisseria gonorrhoeae. The authors of this manuscript describe a cross-sectional multi-site study to determine the prevalence of Neisseria gonorrhoeae and Chlamydia trachomatis in pregnant women and populations at higher risk of sexually transmitted infections (key populations) in Kenya. Neisseria gonorrhoeae prevalence was significantly lower among pregnant women [1.0% (95%CI: 0.5-1.9)] than key populations [9.4% (95%CI: 6.9-12.5)], while Chlamydia trachomatis prevalence was similar for pregnant women [9.6% (95%CI: 7.8-11.7)] and key populations [11.2% (95%CI: 8.4-14.5)]. Neisseria gonorrhoeae and Chlamydia trachomatis prevalence were highest among younger individuals, 5.7% and 15.1% in pregnant women <20 years and 25.0% and 50.0% in key populations <20 years, respectively. Prevalence of both pathogens decreased with increasing age.