Accelerate the discovery of new treatments for life-threatening pandemic diseases by providing researchers free access to 400 diverse compounds.
current phase of drug development
updated 1 Mar 2022
Launched in 2019 by Medicines for Malaria Venture (MMV) and DNDi, the Pandemic Response Box is a collaborative project that aims to accelerate the discovery of new treatments for life-threatening pandemic diseases by providing researchers free access to 400 diverse compounds.
Disease experts selected the Pandemic Response Box’s collection of 201 antibacterial, 153 antiviral, and 46 antifungal compounds for screening against infectious and neglected diseases. The compounds are in various phases of drug discovery or development. In return for receiving the drug-like molecules free of charge, researchers agree to make their screening results publicly available and to publish their findings in an open access journal within two years following data generation.
Graeme Bilbe, Former R&D Director, DNDiThe goal is to help shorten the time between the emergence of a new pandemic and the availability of new drugs to treat it. History has repeatedly shown that saving time, saves lives.
Open and collaborative approaches to medical innovation
The Pandemic Response Box is one of several MMV and DNDi open science projects, which encourage collaboration and transparency in drug development research.
How to order
The Pandemic Response Box is now coordinated by MMV. More details on the box and how to order it can be found on the web page.
Project update
September 2019
In the first 18 months of the project, 116 labs received the Pandemic Response Box, of which 13 are evaluating compounds for activity against COVID-19.
Factsheet
Pandemic Response Box
2019
News & resources
- 14 March 2022 – The pandemic response box ─ accelerating drug discovery efforts after disease outbreaks, ACS Infectious Diseases
- 4 February 2022 – Screening the Pandemic Response Box identified benzimidazole carbamates, olorofim, and ravuconazole as promising drug candidates for the treatment of eumycetoma, PLOS Neglected Tropical Diseases
- 10 November 2021 – How collaboration and new drugs could beat malaria, BBC
- 12 January 2021 – SA researchers may have found a way to cure malaria, The Citizen
- 29 January 2019 – Pandemic Response Box factsheet
- 29 January 2019 – MMV and DNDi create a response box to foster R&D for pandemic diseases, Pharmaceutical Technology
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