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LEAP: 4 Years and Going Strong...

Some of the LEAP Platform's Accomplishments To-date Include:

  • Assessment of regional capacity in R&D for neglected diseases
  • Development of the LEAP 0104 Paromomycin multi-centre clinical trial comparing Paromomycin, Sodium Stibogluconate (SSG), and a combination of Paromomycin and SSG for treatment of VL
  • Two clinical trial sites established in Ethiopia, 2 in Sudan, 1 in Kenya and 1 future site in Uganda
  • Training of clinical monitors, Data and Safety Monitoring Board (DSMB) members and investigators in good clinical practice (GCP)
  • Regular communications network established with a newsletter and biannual meetings
  • Clinical trial capacity strengthening in Ethiopia, Kenya, Sudan, and Uganda
  • Building and opening the leishmaniasis Research and Treatment Centre in Arba Minch, and Gondar, Ethiopia
  • Treatment centre/laboratory training under construction, planned for Dooka (opening in 2008)
  • Capacity strengthening of parasite classification research through technology transfer and training
  • Development and roll-out of national VL treatment guidelines in Ethiopia.

Published by Drugs for Neglected Diseases Initiative - 15 Chemin Louis-Dunant 1202 Geneva Switzerland - Photo credits: DNDi unless otherwise stated - Editor: Sadia Kaenzig - Tel: +41 22 906 9230 - Fax: +41 22 906 9231 -